To determine guidelines for treatment with high-dose intravenous methylprednisolone in lupus nephritis, we prospectively assessed the response to pulse therapy. Single dose steroid (IM or IA) and subsequent risk of osteonecrosis are of particular concern and were examined.
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Multitarget Therapy for Induction Treatment of, lupus, nephritis: A Randomized Trial. Zhihong Liu, MD; Haitao Zhang, MD; Zhangsuo Liu. .
Nephritis can produce glomerular injury, by disturbing the glomerular structure with inflammatory cell proliferation. .
This can lead to reduced glomerular blood flow. .
This article outlines the possible interventions for the complications associated with lupus. .